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Preimplantation Genetic Testing (PGT) has been used in various forms over the last two decades. Preimplantation Genetic Testing PGT involves testing early embryos following in vitro fertilization, IVF, and has now become an accepted part of genetic testing. Nowadays, PGT serves as a resource for couples who have a family history of monogenic (single gene) disorders, wherein the fetus is at high risk of inheriting the condition.
Breastfeeding is the most efficient intervention for reducing infant morbidity and mortality, offering benefits for both infants and mothers. Despite extensive promotion, global adherence remains below 50 %. Breastfeeding offers numerous benefits for both infants and mothers, including providing optimal nutrition and immunological protection for the baby and reducing the risk of certain diseases for the mother.
The vaginal microbiome plays an important role in influencing pregnancy outcome. Dominance of the vaginal niche by Lactobacillus species has been widely reported to be associated with a healthy, full-term pregnancy, specifically Lactobacillus crispatus. In contrast, diverse microbial communities depleted of Lactobacillus species and enriched with bacteria associated with Bacterial Vaginosis; a clinical syndrome characterized by vaginal discharge odor and polymicrobial overgrowth, increases the risk of adverse pregnancy outcomes including miscarriage and preterm birth. Preterm birth represents a significant global health burden.
Since the introduction of pre-implantation genetic testing PGT in assisted reproductive technology, it has become a routine to examine for missing or extra chromosomes known as aneuploidy, genetic disorders, and chromosome structural rearrangements in embryos. These tests are mainly used by couples with advanced maternal age, recurrent pregnancy loss, repeated implantation failure, or a family history of genetic diseases.
The name progesterone is self-explanatory, it is the Pro Gestational Hormone, essential for pregnancy. However, this steroid hormone is far more than a gestational agent. Progesterone is recognized as a key physiological component of not only the menstrual cycle and pregnancy but also as an essential precursor of other gonadal and non-gonadal hormones such as aldosterone, cortisol, estradiol, and testosterone. Based on current findings, progesterone and novel progesterone-based drugs have many important functions, including contraception, treatment of dysfunctional uterine bleeding, immune response, and prevention of cancer.
In the journey of assisted reproductive technology (ART), in-vitro fertilization (IVF) has emerged as a transformative solution for individuals and couples striving to achieve parenthood. Among the various techniques in IVF, Frozen Embryo Transfer (FET) has gained remarkable prominence. Frozen Embryo Transfer, FET involves the cryopreservation of embryos and their subsequent thawing and transfer during a later menstrual cycle. Over the years, FET has demonstrated significant advantages, particularly in yielding higher implantation and pregnancy rates as compared to fresh embryo transfers. This article explores how FET has evolved, the scientific rationale behind its success, and its implications for reproductive medicine.
Infertility is defined by the American College of Obstetricians and Gynecologists as the inability to become pregnant after 12 months or more of unprotected intercourse for women under 35 and after six months for women over 35.
Nature protects you and your child by selecting only the best embryos so that you have the best chance of giving birth to a healthy child. This article will explain the natural selective process and its protective function. Perhaps more importantly we will suggest strategies that can help increase your odds of having a healthy child.
Ovarian cancer is one of the leading causes of cancer deaths among women. A woman's risk of getting ovarian cancer during her lifetime is about 1 in 91. Her lifetime chance of dying from ovarian cancer is about 1 in 143. This cancer mainly develops in older women. About half of the women who are diagnosed with ovarian cancer are 63 years or older.
Preterm birth is defined as any birth that occurs before 37 weeks of gestation and is the leading cause of illness and death among newborns. The 2023 March of Dimes Report Card reveals that more than one in ten infants were born prematurely in the United States in the past five consecutive years and for the third consecutive year, the March of Dimes Annual Report Card has given the United States a D+ for the country’s persistently high preterm birth rate.